In this LM of the connective tissue space supporting the epithelium of the intestine, HA18, in close proximity to plasma (antibody secreting) cells (PC, arrows, 1), you can see a cell with bright red granules in its cytoplasm (arrows, 2). These eosinophils (E), that are named for their intense red stain, are one of the white blood cells. Their cytoplasm is filled with large granules, which are very large lysosomes. Although they appear to have two nuclei, eosinophils have a single, bilobed nucleus (HA24). This image illustrates the concept that cell identity and function can be recognized by the position and shape of the nucleus. This stain, Hematoxylin (blue, basophilic) & Eosin (red, acidophilic), abbreviated H&E, is the most common stain combination you will encounter in histology and pathology images.